Search medications using FDA pregnancy categories (A–X) and evidence-based guidance. Get instant safety verdicts and explanations.
Adequate, well-controlled studies in pregnant women have not shown a risk to the fetus.
Animal studies have not shown a risk, but no adequate studies in pregnant women. Or animal studies show risk, but well-controlled studies in pregnant women have not shown a risk.
Animal studies show risk, but no adequate studies in pregnant women. Or no animal or human studies available. Weigh benefits against risks.
Positive evidence of human fetal risk. Benefits may warrant use despite potential risks.
Studies in animals or humans show fetal risk. Contraindicated in pregnancy.
Organogenesis occurs—fetal organs form. Most medications are Category B, C, or D. Always discuss necessity and risks with your OB/GYN before taking anything.
Organ formation largely complete, but fetal growth continues. Some medications that were avoided in the first trimester may be safer now. Reassess with your provider.
Certain medications (NSAIDs, ACE inhibitors) may affect labor or newborn. Some Category X drugs become acceptable for very specific conditions. Always coordinate with your delivery team.
SSRIs (sertraline, paroxetine) generally Category C. Untreated depression carries risks; discuss with OB/GYN.
Used for high blood pressure, mostly Category C first trimester, D in second/third. Requires monitoring.
Some categories C/D. Risk of seizures if stopped may outweigh drug risk. Discuss with neurologist.
Levothyroxine (Synthroid) Category A. Cannot stop; untreated hypothyroidism harms fetus.
Acetaminophen Category B. NSAIDs typically C, D in third trimester. Avoid if possible.
Penicillins Category B (safe). Avoid tetracyclines (D). Discuss specific antibiotic with doctor.
Albuterol Category C. Uncontrolled asthma poses more risk. Maintain treatment.
In 2015, the FDA replaced letter categories (A–X) with more detailed narrative labeling. Older drugs still use A–X; newer drugs have section 8.1 (Pregnancy) and 8.2 (Lactation) with detailed evidence. Always review your medication's current label and discuss with your healthcare provider.